It's more than 600 miles away, and the results are fairly predictable - the Irish haven't lost a football game to the Navy Midshipmen since 1963.
Nonetheless, Notre Dame students say they are excited to set sail for the land of blue crabs and the Chesapeake Bay and cheer the Irish on to victory.
Senior Chris Peterson is driving the 600 miles to Navy with friends and roommates.
"It's a lot of driving for the weekend, but it will be worth it," Peterson said.
Peterson actually received an appointment to the Academy and considered attending. But his loyalties are not divided - he said he is definitely hoping for an Irish victory.
He is staying with a friend who attends Loyola College in Maryland and hopes to check out Baltimore's inner harbor over the weekend.
Also driving to the game with friends is junior Matt Mattare. Originally from Allentown, Pa., Mattare is meeting up with some friends from home while back on the East Coast.
"My best friend actually goes to Navy," Mattare said. "She is actually cheering for Notre Dame because of me and is going to be sitting with us in the Notre Dame student section. We are going to put her up for pushups every time Notre Dame scores."
Unfortunately, his best friend can't host guests at the Academy - "she's kind of on lockdown," Mattare said. Instead, he's staying with friends at Loyola College.
Before he returns to Notre Dame on Sunday, Mattare said he hopes to experience a little bit of Maryland culture.
"Crab cakes and football, that's what Maryland does. I'm going to have to experience both," he said.
Senior cheerleader Katy Marvin is excited to be making the trip to Maryland with the Fighting Irish squad.
"I feel really lucky I get to fly there," Marvin said.
The Irish will play the Midshipmen in Baltimore at the M&T Bank Stadium - home field of the NFL's Baltimore Ravens.
When the game kicks off on Saturday at 12:12 p.m., Notre Dame will attempt to add another victory to its 42-game winning streak, the longest of its kind in college football. Notre Dame has not lost to Navy since 1963, and leads the series 69-9-1.
